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br Origin of vertebrate CXC chemokine
2020-08-04
Origin of vertebrate CXC chemokine receptors The BMI-1 inhibitor of the vertebrate CXC chemokines and receptors has not been resolved. Based on the evolution of the immune system and central nervous system, Huising et al. proposed that primordial CXC chemokines and receptors developed first as r
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The remainder of this paper is organized as follows Section
2020-08-04
The remainder of this paper is organized as follows: Section 2 provides background on previous research about SE for scientific software. Section 3 describes the research methodology used in this systematic literature review. Section 4 reports the scientists’ and software engineers’ claims about SE
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One may notice however that in the extended CMV matrix
2020-08-04
One may notice, however, that in the extended CMV matrix , whereas in the quantum walk matrix U could be a complex number with non-zero argument, which means that these two matrices may not match. However, this can be easily resolved by conjugation with a suitable diagonal unitary, that is, there
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One may notice however that in the extended CMV matrix
2020-08-04
One may notice, however, that in the extended CMV matrix , whereas in the quantum walk matrix U could be a complex number with non-zero argument, which means that these two matrices may not match. However, this can be easily resolved by conjugation with a suitable diagonal unitary, that is, there ex
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The volatile compounds of various papaya cultivars have been
2020-08-04
The volatile compounds of various papaya cultivars have been extensively investigated (Pino, Almora, & Marbot, 2003). Twenty-five odorants were considered as odour-active compounds and contribute to the typical papaya aroma. The pungent-sour and green-note odours found in the green fruit are due to
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To assess whether the described cooperation between the EGFR
2020-08-04
To assess whether the described cooperation between the EGFR and FGFR receptors was relevant at the clinical level, we determined the effect on progression-free survival of FGFR1 expression in patients with adenocarcinoma who were receiving erlotinib or gefitinib. As we had observed EGFR-FGFR1 coope
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Phosphorylation can also negatively affect DUB activity The
2020-08-04
Phosphorylation can also negatively affect DUB activity. The DUB OTULIN is recruited to the NF-κB pathway by binding the HOIP PUB domain with its PUB Interacting Motif (PIM) 76, 77, thus connecting the E3 ligase (HOIP in the LUBAC complex) and the DUB for linear ubiquitin chains. Phosphorylation of
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br Acknowledgements br Introduction Hydroxy
2020-08-04
Acknowledgements Introduction -Hydroxy-l-arginine (NOHA) is an intermediate in the oxidation of l-arginine to nitric oxide (NO) catalyzed by NO-synthases (NOS) [1], [2]. In mammals, NO is an important mediator that displays key roles in the cardiovascular, nervous and immune systems [3]. NOHA
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br Discussion We show that in rad
2020-08-04
Discussion We show that in rad53-1 mutant cells, synthesis of leading and lagging strands is uncoupled, which leads to the exposure of long stretches of single-stranded leading-strand template coated with RPA under replication stress. We observed that the replicative DNA helicase, MCM, and associ
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Totally three basic interactional means would
2020-08-04
Totally three basic interactional means would happen when small molecules bind to DNA: intercalation, groove binding as well as electrostatic interactions. The structure of the small molecules is a determinative factor for the binding types. A planar and aromatic structure of a molecule prefers to h
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During this period of flux studies there was also
2020-08-03
During this period of flux studies, there was also considerable interest in the regulation of the chloride conductances in apical membrane vesicles from human placenta. It has been suggested that apical membrane chloride conductances are inhibited by protein kinase A-dependent phosphorylation [14] a
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As mentioned above EBI and its ligand show some similarities
2020-08-03
As mentioned above, EBI2 and its ligand show some similarities to the sphingosine 1-phosphate (S1P)/S1P-receptor system, which mediates T cell egress from lymph nodes. Blockade of this system yielded in the first oral drug for MS patients named fingolimod. Therefore, the hope that EBI2 deficiency wo
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br Concluding Remarks and Future Perspectives Ubiquitin liga
2020-08-03
Concluding Remarks and Future Perspectives Ubiquitin ligases serve as central regulatory nodes of signaling pathways and elicit selective functions because they may be (i) mutated/dysfunctional in a tumor [9], (ii) expressed in select tissues, and (iii) target specific substrates in a spatial and
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In Pakistan rice is considered as one of
2020-08-03
In Pakistan, rice is considered as one of the cash crop and about 6 million tonnes of good quality rice produce every year [33]. From the report of researchers, it is concluded that 20% of rice paddy is husk, it means that Pakistan produces nearly 1.2 million tonnes of rice husk every year. Out of 6
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Oxybutynin Several upstream signaling pathways can
2020-08-03
Several upstream signaling pathways can cause an increased expression and activation of eNOS. Vascular endothelial growth factor receptor 3 (VEGFR3) and its specific partner vascular endothelial growth factor C (VEGFC) can activate eNOS activity [23]. The ephrin A1 ligand and its specific receptor,
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